Pemphigus Vulgaris Causes

Pemphigus is an autoimmune disorder. The immune systems create antibodies against particular proteins in the skin and mucus membranes. These antibodies break the bonds between skin cells. This leads to the formation of a blister. The pemphigus vulgaris exact cause is unknown.

Sometimes pemphigus is caused by certain drugs, although this is rare. Medications that may cause this condition include:

  • Blood pressure medications called ACE inhibitors
  • A drug called penicillamine, which removes certain materials from the blood
  • Pemphigus is uncommon. It almost always occurs in middle-aged or older people

Serious cases of pemphigus may need wound management, related to the Pemphigus Vulgaris Treatment for severe burns. People with pemphigus vulgaris condition may need to stay in a hospital and receive care in a burn unit or intensive care unit.

Treatment is aimed at reducing symptoms, including pain. It also aims to stop complications, particularly infections.

Pemphigus Vulgaris Treatment may involve:

  • IV feedings if there are serious mouth ulcers
  • Fluids and electrolytes given through a vein
  • Numbing mouth lozenges to decrease mouth ulcer pain
  • Pain medications if local pain relief is not enough
  • Antibiotics and antifungal medications to control or stop infections