Pemphigus Vulgaris Treatment Guidelines

These guidelines for pemphigus vulgaris have been organize for dermatologists on behalf of the British Association of Dermatologists. They present verification based guidance for Pemphigus Treatment, with identification of the strength of evidence available at the time of preparation of the guidelines, and a brief overview of epidemiological aspects, diagnosis and research.

The primary aim of Treatment of Pemphigus Vulgaris is to reduce blister formation, stop infections and help healing of blisters and erosions. Oral corticosteroids are the mainstay of medical treatment for controlling the disease. Because their use, several deaths from pemphigus vulgaris have been prevented mortality rate dropped from 99% to 5-15%. They are not a cure for the disease but recover the patient's quality of life by reducing disease activity. Unfortunately higher doses of corticosteroids may result in severe side effects and risks. Other immune suppressive drugs are used to minimize steroid utilize.

Patients should reduce activities that may traumatise the skin and mucous membranes during active phase of the disease. These consist of activities such as contact sports, eating and drinking food that may irritate or damage the inside of the mouth (spicy, acidic, hard and crunchy foods).