Motor Neuron Disease
Motor Neuron Disease is a group of diverse conditions which is normally characterized by worsening of lower motor neurons that have cell bodies in cranial nerve nuclei and synapse directly on muscle or upper motor neurons that have cell bodies in the brain and synapse in lower motor neurons.
What is Motor Neuron Disease?
Motor Neuron Disease usually refers to amyotrophic lateral sclerosis, but it can also refer to other kind of neurodegenerative disease that affects the motor neurons, such as progressive primary lateral sclerosis, progressive muscular atrophy and progressive bulpar palsy.
People with Motor Neuron Disease experience a wide range of symptoms, including a number of physical ability limitations, pain, spasticity, cramps, swallowing problems and difficulty breathing. Motor neuron diseases are characterized by selective degeneration of motor neurons, both upper and lower, namely of the pyramidal fibers in cerebral cortex, of ventral horn cells and of cranial motor nerve nuclei. In different cases relative incidence of degeneration varies.
Key Facts of Motor Neuron Disease
- A group of neurological disorders.
- Motor neurons are affected which are responsible for carrying voluntary muscle actions.
- Increases disability with every day that passes because it is generally progressive.
- Causes death in severe cases.
- The ability to control voluntary movement deteriorates progressively.
- Can occur in all age groups.
- More common in men than women.
- Symptoms normally appear after the age of 40.
- Frequent fasciculations i.e. uncontrolled twitching is quite common in persons suffering from this disorder.
- It is classified into 5 different disorder which are listed here:
Amyotrophic lateral sclerosis (ALS)
Primary lateral sclerosis (PLS)
Progressive muscular atrophy (PMA)
Progressive bulbar palsy (PBP)
- Amyotrophic lateral sclerosis is the most common form of MND (Motor Neurone Disease).
Causes of Motor Neuron Disease
The Causes of Motor Neuron Disease have still not been noticeably identified by researchers and medical specialists. It is believed that inheritance play main role in the occurrence of Motor Neuron Diseases. Sometimes these diseases have been expected as happening due to as serious genetic influence.
About 5% of people with motor neurone disease have a close family relative with the condition or a connected condition known as frontotemporal dementia. This is called familial motor neurone disease which can be hereditary or connected to a problem with genes that can Causes of Motor Neuron Disease problems at a younger age.
Symptoms of Motor Neuron Disease
There are some very evident Symptoms of Motor Neuron Disease which make the identification easier. Some of these that authorize the presence of this disease include:
- Breathing difficulty
- Abnormal speech pattern
- Climbing difficulty
Symptoms of Motor Neuron Disease come on slowly and may not be obvious at first.
Early Symptoms of Motor Neuron Disease can include:
- Muscle cramps and twitches
- Weakness in your ankle or leg you might trip or find it harder to climb stairs
- Slurred speech which may grow into difficulty swallowing some foods
- A weak grip you might drop things or find it hard to open jars or do up buttons
- Weight loss your arms or leg muscles may have become thinner over time
- Difficulty stopping yourself crying or laughing in inappropriate conditions
Diagnosis of Motor Neuron Disease
It can be difficult to diagnose motor neurone disease in the initial stages. There's no single test for it and some conditions cause similar symptoms. Another common test is a nerve conduction study which assesses a nerve's ability to send a signal. Other tests that may be used to help with the Diagnosis of Motor Neuron Disease and rule out other causes for the symptoms include:
To help rule out further conditions a neurologist may arrange:
- Blood tests
- A scan of your brain and spine
- Tests to measure the electrical activity in your muscles and nerves
A lumbar puncture also called a spinal tap – when a thin needle is used to eliminate and test the fluid from within your spine.
Prognosis of Motor Neuron Disease
Prognosis of Motor Neuron Disease varies depending on the type of MND and the age of onset. Some MNDs for example PLS or Kennedy’s disease, are not fatal and progress slowly. People with SMA may look to be stable for long periods but improvement should not be expected. Some MNDs for example ALS and some forms of SMA, are fatal.
- It is rare to survive beyond five years from diagnosis
- Motor neurone disease is deadly but the progression is variable
- The best indicator is how rapidly a person is diagnosed the longer this takes, the longer they are possible to survive
Complications of Motor Neuron Disease
Complications come from weakness in important muscles groups
- Respiratory failure
- Respiratory muscle connection causes type II respiratory failure with symptoms of breathlessness on exertion or when lying flat
- Examination: Poor inspiratory effort absence of abdominal movement with respiration and even the bounding pulse of CO2 retention
- Investigations: Gradually climbing carbon dioxide levels on arterial blood gas
- CXR showing raised hemi-diaphragm
- EMG of the intercostal or diaphragm showing denervation
- The only treatment is to provide ventilation support in the form of non-invasive ventilation
Key Point of Motor Neuron Disease
Key Point of Motor Neuron include:
- MND can be quickly progressive and has no cure so all care and support for people with the condition must be timely and is essentially palliative.
- Initial support from specialist palliative care services can make a huge difference to quality of life
- Life expectancy after diagnosis ranges from 3 years to longer than 10 years
- People should be given opportunities to discuss and record preferences for the end of their life before the need is urgent their ability to communicate is limited or they find it too tiring
- Symptoms should be managed in line with the wishes of the person with MND to ensure they have the best possible quality of life
Why do you think you should go for dietary herbal supplement?
You should go for dietary herbal supplement because:
- Made of natural ingredients.
- Packaged safely in air tight jars.
- Superior quality.
- Offer great value for money.
Here is a list of ingredients used in this dietary herbal supplement for your reference:
- Wattle Bark 116.27mg
- Elephant Creeper 58.11mg
- Sweet Root 58.13mg
- Coral Calcium 34.88mg
- Iron Compound 34.88mg
- Spanish Chamomile 23.25mg
- Cloves 23.25mg
- Vermilion 23.25mg
- Indian Bay-leaf 23.25mg
- Nutmeg 23.25mg
- The herbal pill is intended for oral use only.
- Take 2 tablets each day in the morning after breakfast and evening after dinner.
- Fix times for daily intake and follow precisely.
- Be regular to witness the most results.
Here we have some old school tips compiled for you to take advantage from. We will keep updating them as soon as we come up with something new through experiment. In the meanwhile read and follow these:
- Unfortunately there are no home remedies that can be of help to eradicate or ease out the symptoms.
- All these tips will keep you motivated and make you feel good about yourself while you are still undergoing the Motor Neuron Disease management routine with our Herbal Alternative Medicine.
- These tips and tricks are by no means a replacement of actual products.